A win for Jamie Clapham's side would have seen them leapfrog the Black Country outfit and move into second place in the Barclays Premier U21 table.
In driving rain Boro, playing their second away game in five days, soon got into their passing style, which has been a trademark of their games so far this season. They fashioned the first chance of the game on 10 minutes, when a driving run from Luke Williams saw him brought down 20 yards out. The pacey forward took the free kick but saw his effort go straight at the keeper.
Three minutes later Lewis Sirrell cut in from the right wing onto his favoured left foot, but his shot went wide of the target.
Boro were enjoying the majority of possession now and Wolves were struggling to get out of their half. On 14 minutes Christian Burgess nearly got his head to a Ryan Brobbel corner but was foiled by a last ditch defensive header from Ihiekwe.
Skipper Matty Dolan was prominent in the centre of the park, winning the ball and releasing it to the wings. But he was booked in the 20th minute after a rash challenge on highly rated Zeli Ismail.
Brobbel went close with a spectacular effort on 25 minutes after a great flick from Sirrell, but his 25-yard first-time shot went just wide.
Boro were starting to create chances at will now and Williams drove forward from the halfway line, but his shot was blocked by the keeper as he advanced into the area. Unfortunately he limped off due the challenge and was replaced by Jimmy Warnett, who was making his U21 debut.
Wolves tried to hit back on 32 minutes and after Gorman fizzed in a left wing cross, Burgess cleared over his own bar.
Warnett was making an immediate impact and created two chances but saw both his efforts go off target.
On 41 minutes the booking total was equalised when Zubar cynically brought down Brobbel, after an audacious piece of skill saw him turn the big central defender.
The half came to a close with Ripley superbly tipping over a 20 yard shot from Nouble.
Half time: Wolves U21s 0 Boro U21s 0
The second half started in the same vein as the first with Boro enjoying the lion's share of possession.
Matty Waters had a shot saved on 63 minutes after a good run, but then Wolves had their best spell of the game, as they started to press forward.
Ripley was brought into action again on 66 minutes after a snap shot from Jakobsson. Five minutes later Nouble bustled his way into the area and was foiled by the big keeper.
As the game moved into the last five minutes, Boro started to press again and a great 50 crossfield ball from Brobbel found substitute Jake Fowler. His first-time lob just cleared the bar with the keeper stranded.
Curtis Edwards then shot wide before it looked like Fowler had won the game, only to see his shot go inches wide.
Just before the close Kyle Oliver put in a great clearing header, after a right wing cross from Ismail, as Boro gained a hard fought point.
Boro: Ripley; Bennett, Weldon, Dolan (Capt), Burgess, Oliver, L Williams (Warnett 29), Brobbel, Waters (Fowler 68), Kneeshaw (Edwards 46). Unused subs: Bland (gk), Rivers.
Wolves: McCarey; Kostma (Parry 78), Cranston, Jakobsson, Ihiekwe, Zubar, Ismail, Price, McAlinden, Nouble (Kellerman 86), Gorman (Whittall 61). Unused sub: Tank
Bookings: Dolan (20 mins) - Foul on Ismail, Zubar (41 mins) - Foul on Brobbel
Boro MoM: Plenty of good performances all over the park. The back four were all solid against a physical forward line, while Connor Ripley made some excellent saves when called upon. However the award goes to Ryan Brobbel, who was a constant thorn in the Wolves back line with his driving runs and trickery.