Callum Cooke scored his second goal for Crewe Alexandra in Saturday's 2-1 loss to Newport County.
The winger tucked home from inside the area after 22 minutes to give his side the lead. But after the break, bottom club County hit back with goals from Dan Butler and Joss Labadie to give caretaker boss Mike Flynn the perfect start.
Joe Fryer saved a penalty, but couldn't prevent Hartlepool's defeat to Notts County.
Fryer denied veteran striker Shola Ameobi from the spot in the first half, but the Nigerian forward made amends with a low strike early in the second period.
The hosts doubled their lead in emphatic fashion thanks to a 20-yard piledriver from Nottingham Forest loanee Jorge Grant - and though Pools pulled a goal back when Haydn Hollis put the ball into his own net, it was not enough as Kevin Nolan's Magpies held on to all three points.
Connor Ripley kept his fifteenth clean sheet of the season as Oldham played out a goalless draw with Bury.
Ripley was called upon to twice deny Bury sub George Miller in the game's closing stages, with the North West rivals now both positioned just above the League One relegation zone.
Julien de Sart played 45 minutes for Derby as their play-off hopes were dealt a blow at Brighton.
Anthony Knockaert, Sam Baldock and Glenn Murray scored for Albion in a result that ultimately cost Steve McClaren his job - the former Boro boss parted company with the Rams for the second time on Sunday.
Harry Chapman featured for Sheffield United Under-23s as he continues his return from long-term injury, and provided an assist in the side's win against Bolton.