Jay Simpson had put Hull ahead, but a close-range double salvo from McDonald turned the game Boro's way.

Julio Arca grabbed a third for Boro before McDonald wrapped up his hat-trick and the match before the break, Anthony Gerrard late netting another for Hull but not enough to trouble Boro.

The win dented Hull's play-off ambitions while also mathematically ensuring Tony Mowbray's Boro side retained their Championship status.

Watch highlights from the game in the video player above.