Just three days after drawing 0-0 away to Blackburn the squad make the long journey down to Carrow Road to take on Norwich City.
"We have always said that we wanted Academy football to have a schedule like first team football and this is the type of thing that can happen," says Lead Coach Paul Jenkins.
The game was scheduled to be played next Monday, but had to be switched as Boro are involved in a game away to Scunthorpe in the Checkatrade Trophy on Tuesday night.
Both league games have been goalless draws for Jenkins' side, the Blackburn game following on from an opening day stalemate with Brighton.
"We're building the foundations, the one thing we now need to improve on is in the final third. At some stage we're going to have to stick the ball in the net.
"If I was asked what I want against Norwich, goals would be the answer."
Boro will be without Nathan McGinley as he tore a hamstring at Leyland on Monday, while an assessment will be made on Joao Morelli following his first game of the season.
"It's good to see him [Morelli] back, but he needs minutes," said Jenkins. "He was on his knees at the end of the game on Monday. We won't just give him token minutes though, he needs to earn a place in the side.
"We are going to have to go again with the intensity shown against Blackburn. Anything less and we may suffer."
Kick-off at Carrow Rad is 7pm.